What is it about?

A review in oncolytic virus delivery platforms, materials, nano particles, that can enhance intra tumor spread by minimizing or balancing the tumor microenvironment heterogeneity

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Why is it important?

The ultimate frontier to oncolytic virotherapy in beyond vector development. It is necessary that the vector reach the tumor and spread within the tumor without being neutralized by the immune system. To date a systemic approach is not yet feasible due to delivery matters.

Perspectives

This review summarizes what strategies have been made to a better delivery system.

Raquel Yokoda
Mayo Clinic

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This page is a summary of: Oncolytic virus delivery: from nano-pharmacodynamics to enhanced oncolytic effect, Oncolytic Virotherapy, November 2017, Dove Medical Press,
DOI: 10.2147/ov.s145262.
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