What is it about?
In this study we used the Odyssey platform to develop an in vivo imaging paradigm that allows a rapid and long-term realtime detection of grafted stem cells in living rats. After validating our labeling in vitro we observed that cells could be detected and mapped correctly both in living animals and after sacrifice.
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Why is it important?
This study demonstrates that our staining method constitutes an effective, safe and non-invasive method to monitor in vivo grafted stem cells. This procedure enables real time evaluation of stem cell distribution after transplantation and will support the development of efficient therapeutic strategies promptly applicable to patients.
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This page is a summary of: Noninvasive near-infrared live imaging of human adult mesenchymal stem cells transplanted in a rodent model of Parkinson’s disease, International Journal of Nanomedicine, January 2012, Taylor & Francis,
DOI: 10.2147/ijn.s27537.
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