What is it about?
Nosocomial infections due to vancomycin-resistant enterococci (VRE) are known as a source of spreading these bacteria. In this study we surveyed presence of vanA and vanB genes among VRE isolated from patients admitted to intensive care units (ICUs) in Ahvaz in southwest of Iran. In among of 59 vancomycin-resistant or semi-susceptible Enterococcus isolates, vanA gene was detected in 54 (91.5%) isolates, while none of the isolates had vanB gene.
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Why is it important?
Because of Enterococci containing vanA gene are highly resistant to vancomycin and teicoplanin antibiotics, while enterococci containing vanB gene show high resistance to vancomycin and susceptibility to teicoplanin. Transfer of resistance genes horizontally among the epidemic clones of these bacteria has been reported in many research works.
Perspectives
I hope the clinical laboratories and medical communities consider the importance of vancomycin as a bactericidal antibiotic in the treatment of bacterial infections and by detection of resistant strains and proper treatment of infected patients, resistance development to vancomycin be prevented.
Mojtaba Moosavian
Ahvaz Jondishapour University of Medical Sciences
Read the Original
This page is a summary of: Molecular detection of vanA and vanB genes among vancomycin-resistant enterococci in ICU-hospitalized patients in Ahvaz in southwest of Iran, Infection and Drug Resistance, November 2018, Dove Medical Press,
DOI: 10.2147/idr.s177886.
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