What is it about?
Objective: To determine the prevalence of rifampicin-resistant M. tuberculosis among tuberculosis- presumptive cases at the University of Gondar Hospital. Results: A total of 1,820 M. tuberculosis-presumptive patients were included in the study. The majority of the study participants were males (59.2%). The mean age of the participants was 36.6±15.8 years. The preponderant age-group was 24–30 years, with 477 (23.5%) patients. The overall prevalence of M. tuberculosis-confirmed cases was 448 (24.6%, 95% CI 0.23–0.27). Of the 448 M. tuberculosis-confirmed cases, 71 (15.8%, 95% CI 1.12–1.19) were resistant to rifampicin. Rifampicin-resistant M. tuberculosis was observed among HIV seropositive (14 [18.7%]), males (45[17.3%]), and previously treated tuberculosis patients (61 [16.5%]), although no significant association was found in this study. Conclusion: The overall prevalence of M. tuberculosis and rifampicin resistance was found to be high in tuberculosis patients in this study. Therefore, early detection of drug-resistant M. tuberculosis should be strengthened for management of tuberculosis patients.
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Why is it important?
Determining the prevalence is important for early detection of drug-resistant M. tuberculosis and strengthen management of tuberculosis patients.
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This page is a summary of: Rifampicin-resistant Mycobacterium tuberculosis among tuberculosis-presumptive cases at University of Gondar Hospital, northwest Ethiopia, Infection and Drug Resistance, June 2017, Dove Medical Press,
DOI: 10.2147/idr.s135935.
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