What is it about?
The study seeks to compare the safety and tolerability of artemisinin-based antimalarias in second and third trimester of pregnancy. In this study it was observed that elevation of liver enzymes were not clinically significant and no new safety concerns was associated with the use of the drugs in pregnancy. The drugs are therefore safe for prescription and use in pregnancy.
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Perspectives
The study seeks to compare the safety and tolerability of artemisinin-based antimalarias in second and third trimester of pregnancy. In this study it was observed that elevation of liver enzymes were not clinically significant and no new safety concerns was associated with the use of the drugs in pregnancy. The drugs are therefore safe for prescription and use in pregnancy.
Dr Osede Ignis Iribhogbe
Ambrose Alli University EKpoma Edo State Nigeria
Read the Original
This page is a summary of: Comparative analysis of the safety and tolerability of fixed-dose artesunate/amodiaquine versus artemether/lumefantrine combinations for uncomplicated falciparum malaria in pregnancy: a randomized open label study, Clinical Pharmacology Advances and Applications, May 2017, Dove Medical Press,
DOI: 10.2147/cpaa.s131351.
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