What is it about?
Whole body exercise induces alterations in lymphocyte subset percentages in peripheral blood in young healthy men both before and after antioxidants. Resistive breathing, namely breathing through an inspiratory resistance, produces similar alterations that are blunted after the administration of antioxidants.
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Why is it important?
Resistive breathing, a hallmark of diseases of airway obstruction, is a form of exercise for the inspiratory muscles. We have shown for the first time that inspiratory resistive breathing induces lymphocyte subset alterations through an oxidative stress-dependent pathway. Lymphocytes are key immune cells that regulate both innate and adaptive immunity. Increased airway resistance may not only induce inflammation and lung injury, but also precipitate, through oxidative stress, peripheral immune alterations
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This page is a summary of: Immune cell response to strenuous resistive breathing: comparison with whole body exercise and the effects of antioxidants, International Journal of Chronic Obstructive Pulmonary Disease, February 2018, Dove Medical Press,
DOI: 10.2147/copd.s154533.
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