What is it about?
Severe exacerbations associated with chronic obstructive pulmonary disease (COPD) that require hospitalization significantly contribute to morbidity and mortality. Definitions for exacerbations are very broad, and it is unclear whether there is one predominant underlying mechanism that leads to them.
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Why is it important?
Functional respiratory imaging (FRI) with modeling provides detailed information about airway resistance, hyperinflation, and ventilation-perfusion (V/Q) mismatch during and following an acute exacerbation.
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This page is a summary of: Changes in ventilation–perfusion during and after an COPD exacerbation: an assessment using fluid dynamic modeling, International Journal of Chronic Obstructive Pulmonary Disease, March 2018, Dove Medical Press,
DOI: 10.2147/copd.s153295.
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