What is it about?
Different prediction models have been developed that can give individual dialysis patients a risk estimate for death. However, none of these models are used in everyday practice. Partly due to the fact that they have not been tested in different dialysis populations, so we are unsure on how accurate they are in predicting death. This article provides an overview of all existing models, and tests these models in the same group of Dutch dialysis patients.
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Why is it important?
The manuscript shows that prediction models perform poorer in validation than the original papers suggest. The manuscript provides support for clinicians in choosing a model that is best suited for their patient population.
Perspectives
This publication contains an important clinical message, on how and which prediction model to use in patient consultations. Besides that it also has epidemiological value in serving as an example of a comprehensive validation study, of which many more are necessary in the medical field in order to combat research waste.
Chava Ramspek
Leiden University Medical Center
Read the Original
This page is a summary of: Prediction models for the mortality risk in chronic dialysis patients: a systematic review and independent external validation study, Clinical Epidemiology, September 2017, Dove Medical Press,
DOI: 10.2147/clep.s139748.
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