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Prognosticators of Packed Red Blood Cell Transfusion in Patients Undergoing Off-Pump Coronary

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Background: Coronary revascularization surgery is a procedure associated with higher rate of transfusion. Approximately 20% of all cardiac surgeries require allogeneic blood transfusions. The Red Blood Cells (RBCs) transfusion increases the morbidity and mortality in any surgery. The understanding of preoperative variables pertinent with the Red Blood Cells (RBCs) transfusion will authenticate the risks of transfusion and thus cede the need for productive blood conservancy methods. The intention of this study was to regulate the clinical and demographic variables associated with blood product transfusion in patients undergoing elective off pump coronary revascularization surgery. Materials and Methods: This was a single-center retrospective study conducted on 142 patients who had undergone elective off pump coronary revascularization surgery Patients’ preoperative clinical and demographic data, were analyzed. The preoperative lab analysis like hemoglobin, hematocrit, renal functions and coagulation profile were cataloged. The primary endpoints of interest was packed red blood cell transfusion. Secondary outcomes analyzes were reoperation rate for bleeding or cardiac tamponed and total postoperative chest tube drainage. Only intraoperative and postoperative (6 days) homologous packed RBC transfusions were recorded. Results: A total of 142 patients who underwent isolated off pump coronary revascularization surgery were studied. Blood transfusions were given to 23 of 142 patients (16.19%). Eleven of 41 women (26.8%) needed transfusion, compared with 12 of 101 men (11.9%) (p < 0.028). Conclusion: In the present study, we conclude preoperative anemia, low hematocrit and female gender were certainly associated with perioperative allogeneic red blood cells transfusion in patients undergoing off pump coronary revascularization surgery.

Perspectives

Background: Coronary revascularization surgery is a procedure associated with higher rate of transfusion. Approximately 20% of all cardiac surgeries require allogeneic blood transfusions. The Red Blood Cells (RBCs) transfusion increases the morbidity and mortality in any surgery. The understanding of preoperative variables pertinent with the Red Blood Cells (RBCs) transfusion will authenticate the risks of transfusion and thus cede the need for productive blood conservancy methods. The intention of this study was to regulate the clinical and demographic variables associated with blood product transfusion in patients undergoing elective off pump coronary revascularization surgery. Materials and Methods: This was a single-center retrospective study conducted on 142 patients who had undergone elective off pump coronary revascularization surgery Patients’ preoperative clinical and demographic data, were analyzed. The preoperative lab analysis like hemoglobin, hematocrit, renal functions and coagulation profile were cataloged. The primary endpoints of interest was packed red blood cell transfusion. Secondary outcomes analyzes were reoperation rate for bleeding or cardiac tamponed and total postoperative chest tube drainage. Only intraoperative and postoperative (6 days) homologous packed RBC transfusions were recorded. Results: A total of 142 patients who underwent isolated off pump coronary revascularization surgery were studied. Blood transfusions were given to 23 of 142 patients (16.19%). Eleven of 41 women (26.8%) needed transfusion, compared with 12 of 101 men (11.9%) (p < 0.028). Conclusion: In the present study, we conclude preoperative anemia, low hematocrit and female gender were certainly associated with perioperative allogeneic red blood cells transfusion in patients undergoing off pump coronary revascularization surgery.

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This page is a summary of: Prognosticators of Packed Red Blood Cell Transfusion in Patients Undergoing Off Pump Coronary Revascularization, Indian Journal of Anaesthesia and Analgesia, January 2020, Red Flower Publication Private, Ltd.,
DOI: 10.21088/ijaa.2349.8471.7120.21.
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