What is it about?

Effect of I.V. Ketorolac Versus I.V. Tramadol in Pediatric Inguinal Herniotomy and Penile Surgeries

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Why is it important?

Pre-emptive analgesia aims at preventing central nervous system from reaching the hyper excitable state known as central sensitization, in which it responds excessively to afferent inputs. The effective pain management pre-operatively can reduce the post-operative pain and analgesic requirement in pediatric age group. Inguinal hernia repair and penile surgeries are one of the most common and painful ambulatory surgeries with 40–50% patients reporting moderate to severe pain within 24 hours. Hence it is the prime concern of anesthesiologist for post-operative pain relief. Our study was conducted in 60 patients of ASA Grade I/II aged between 2–8 years, who were randomly divided into two Groups, Group K and Group T. We used intravenous ketorolac 1 mg/kg body weight and tramadol 1 mg/kg body weight as pre-emptive analgesics and compared intra-operative parameters like mean heart rate, mean arterial pressure, post-operative pain with FLACC score (face, legs, activity, cry, consolability) and time for first rescue analgesia. The study results showed that both the groups were comparable in various demographic data. In our study, intra-operative mean heart rate and mean arterial pressure were significantly higher in case of ketorolac as compared to tramadol. Our results showed that FLACC score is significantly higher and time for first rescue analgesia is significantly earlier in ketorolac group compared with tramadol group. The mean time for first rescue in Group T and Group K was 5.50 ± 0.68 (hours) and 2.33 ± 0.76 (hours) respectively.

Perspectives

Pre-emptive analgesia aims at preventing central nervous system from reaching the hyper excitable state known as central sensitization, in which it responds excessively to afferent inputs. The effective pain management pre-operatively can reduce the post-operative pain and analgesic requirement in pediatric age group. Inguinal hernia repair and penile surgeries are one of the most common and painful ambulatory surgeries with 40–50% patients reporting moderate to severe pain within 24 hours. Hence it is the prime concern of anesthesiologist for post-operative pain relief. Our study was conducted in 60 patients of ASA Grade I/II aged between 2–8 years, who were randomly divided into two Groups, Group K and Group T. We used intravenous ketorolac 1 mg/kg body weight and tramadol 1 mg/kg body weight as pre-emptive analgesics and compared intra-operative parameters like mean heart rate, mean arterial pressure, post-operative pain with FLACC score (face, legs, activity, cry, consolability) and time for first rescue analgesia. The study results showed that both the groups were comparable in various demographic data. In our study, intra-operative mean heart rate and mean arterial pressure were significantly higher in case of ketorolac as compared to tramadol. Our results showed that FLACC score is significantly higher and time for first rescue analgesia is significantly earlier in ketorolac group compared with tramadol group. The mean time for first rescue in Group T and Group K was 5.50 ± 0.68 (hours) and 2.33 ± 0.76 (hours) respectively.

Red Flower Publication Publications
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This page is a summary of: To Compare the Pre-emptive Analgesic Effect of I.V. Keterolac Versus I.V. Tramadol in Pediatric Inguinal Herniotomy and Penile Surgeries, Indian Journal of Anaesthesia and Analgesia, January 2019, Red Flower Publication Private, Ltd.,
DOI: 10.21088/ijaa.2349.8471.6619.10.
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