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Propofol with Butorphanol for Total Intravenous Anaesthesia in Short Surgical Procedures
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Why is it important?
Context: Maintaining hemodynamic stability, reducing pain on injection with Propofol and preventing PONV, in TIVA technique is a contentious subject and there is no perfect method to reduce it. Aims: To compare propofol with ketamine and propofol with butorphanol for total intravenous anesthesia in short surgical procedures. Settings and design: Hospital based study was carried out at SVS Medical College, Mahabubnagar. Methods: Total of 60 patients was studied. They were of either sex and the age ranged from 18-60 years. They had ASA-I & ASA-II grade. Two groups of patients were created randomly. Group K, received PropofolKetamine and Group B, Propofol Butorphanol. Both the groups were induced with Propofol 1.5 mg/kg IV and maintained with Propofol 9 mg/kg/hr IV. Statistical analysis: Chi square test and student’s t test were used. Results: The SBP and DBP fell in both groups of patients after induction. SBP & DBP differed significantly during various intervals in patients who belonged to Group B. Such a significant difference was not found in group K. Pain on injection with Propofol was not attenuated by Butorphanol pre-treatment rather than Ketamine. Post-operative sedation was more in Group B (Propofol-Butorphanol) than in Group K (Propofol –Ketamine). Both the groups were found to be comparable in terms of post operative nausea and vomiting. Conclusion: “Propofol-Ketamine (Group K) combination” has been found to be more effective than the other group of patients who belonged to Group B in terms of stability of the hemodynamic parameters as well as sedation was lesser after surgery
Perspectives
Context: Maintaining hemodynamic stability, reducing pain on injection with Propofol and preventing PONV, in TIVA technique is a contentious subject and there is no perfect method to reduce it. Aims: To compare propofol with ketamine and propofol with butorphanol for total intravenous anesthesia in short surgical procedures. Settings and design: Hospital based study was carried out at SVS Medical College, Mahabubnagar. Methods: Total of 60 patients was studied. They were of either sex and the age ranged from 18-60 years. They had ASA-I & ASA-II grade. Two groups of patients were created randomly. Group K, received PropofolKetamine and Group B, Propofol Butorphanol. Both the groups were induced with Propofol 1.5 mg/kg IV and maintained with Propofol 9 mg/kg/hr IV. Statistical analysis: Chi square test and student’s t test were used. Results: The SBP and DBP fell in both groups of patients after induction. SBP & DBP differed significantly during various intervals in patients who belonged to Group B. Such a significant difference was not found in group K. Pain on injection with Propofol was not attenuated by Butorphanol pre-treatment rather than Ketamine. Post-operative sedation was more in Group B (Propofol-Butorphanol) than in Group K (Propofol –Ketamine). Both the groups were found to be comparable in terms of post operative nausea and vomiting. Conclusion: “Propofol-Ketamine (Group K) combination” has been found to be more effective than the other group of patients who belonged to Group B in terms of stability of the hemodynamic parameters as well as sedation was lesser after surgery
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This page is a summary of: Comparative Study of Propofol with Ketamine and Propofol with Butorphanol for Total Intravenous Anaesthesia in Short Surgical Procedures, Indian Journal of Anaesthesia and Analgesia, January 2019, Red Flower Publication Private, Ltd.,
DOI: 10.21088/ijaa.2349.8471.6319.23.
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