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Efficacy of Caudal Ropivacaine Vs Bupivacaine in Paediatric Population

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Introduction: Caudal anaesthesia has formed a “Corner Stone” in paediatric regional anaesthesia. Bupivacaine is commonly used for caudal analgesia. Newer drugs like Ropivacaine is more cardio-stable and produces less motor blockade hence safer in paediatric age group. Methodology: This study was conducted at a tertiary care setting on 60 ASA 1 & 2 children posted for elective sub-umbilical surgeries. After thorough pre-anaesthetic evaluation, General Anaesthesia was administered followed by Caudal procedure with administration of Ropivacaine (R) or Bupivacaine (B) 1 ml/kg of 0.25% each. Motor blockade and Pain Scores were assessed using Modified Bromage Scale and Objective Pain Score respectively. Rescue analgesics were supplemented accordingly. Results: Haemodynamic parameters, pain score and duration of caudal analgesia were comparable in the 2 groups. Motor blockade in the immediate post-recovery period had a mean value of 1.80 ± 0.66 in group R and 2.47 ± 0.51 in Group B with a p<0.01 and was statistically significant. At 4th hr post-operatively, Group R had no motor blockade whereas Group B had a score of 0.17 ± 0.38 with a p<0.019 and statistically significant. Conclusion: Caudal Ropivacaine offers less motor blockade compared to Bupivacaine and is safe for paediatric population.

Perspectives

Introduction: Caudal anaesthesia has formed a “Corner Stone” in paediatric regional anaesthesia. Bupivacaine is commonly used for caudal analgesia. Newer drugs like Ropivacaine is more cardio-stable and produces less motor blockade hence safer in paediatric age group. Methodology: This study was conducted at a tertiary care setting on 60 ASA 1 & 2 children posted for elective sub-umbilical surgeries. After thorough pre-anaesthetic evaluation, General Anaesthesia was administered followed by Caudal procedure with administration of Ropivacaine (R) or Bupivacaine (B) 1 ml/kg of 0.25% each. Motor blockade and Pain Scores were assessed using Modified Bromage Scale and Objective Pain Score respectively. Rescue analgesics were supplemented accordingly. Results: Haemodynamic parameters, pain score and duration of caudal analgesia were comparable in the 2 groups. Motor blockade in the immediate post-recovery period had a mean value of 1.80 ± 0.66 in group R and 2.47 ± 0.51 in Group B with a p<0.01 and was statistically significant. At 4th hr post-operatively, Group R had no motor blockade whereas Group B had a score of 0.17 ± 0.38 with a p<0.019 and statistically significant. Conclusion: Caudal Ropivacaine offers less motor blockade compared to Bupivacaine and is safe for paediatric population.

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This page is a summary of: Efficacy of Caudal Ropivacaine Vs Bupivacaine in Paediatric Population, Indian Journal of Anaesthesia and Analgesia, January 2019, Red Flower Publication Private, Ltd.,
DOI: 10.21088/ijaa.2349.8471.6219.46.
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