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A Comparative Study of Plain and Hyperbaric Solutions of Bupivacaine HCl During Spinal Anaesthesia
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Background: Spinal anesthesia is often used for both elective and emergency surgeries. Anesthesia-related mortality is decreased when general anesthesia is avoided. Aim: To compare the anaesthetic behaviour and haemodynamic consequences produced by the intrathecal injections of plain and hyperbaric solutions of Bupivacaine with the patients in supine horizontal position. Materials and methods: Sixty patients of ASA I – II were divided into 2 groups of 30 each. Group-A was given 3 ml. of -0.5% plain Bupivacaine sub arachnoidally whereas Group-B was given 3 ml. of 0.5% hyperbaric Bupivacaine. Results: It was found that extent of sensory blockade was much higher in Group-B as compared to Group-A. The degree of motor blockade was also much more intense in Group-B as compared to Group-A. The duration of analgesia was more in Group-A as compared to Group-B, but the time onset of analgesia was faster in Group-B (hyperbaric). Haemodynamically patients in Group-A were stable due to lesser extent of sympathetic blockade when compared to patients in Group-B. Conclusion: Plain Bupivacaine gives a lesser cephalad spread and can be effectively used for lower limb surgeries, it has to be used with caution for lower abdominal surgery as the spread is relatively unpredictable.
Perspectives
Background: Spinal anesthesia is often used for both elective and emergency surgeries. Anesthesia-related mortality is decreased when general anesthesia is avoided. Aim: To compare the anaesthetic behaviour and haemodynamic consequences produced by the intrathecal injections of plain and hyperbaric solutions of Bupivacaine with the patients in supine horizontal position. Materials and methods: Sixty patients of ASA I – II were divided into 2 groups of 30 each. Group-A was given 3 ml. of -0.5% plain Bupivacaine sub arachnoidally whereas Group-B was given 3 ml. of 0.5% hyperbaric Bupivacaine. Results: It was found that extent of sensory blockade was much higher in Group-B as compared to Group-A. The degree of motor blockade was also much more intense in Group-B as compared to Group-A. The duration of analgesia was more in Group-A as compared to Group-B, but the time onset of analgesia was faster in Group-B (hyperbaric). Haemodynamically patients in Group-A were stable due to lesser extent of sympathetic blockade when compared to patients in Group-B. Conclusion: Plain Bupivacaine gives a lesser cephalad spread and can be effectively used for lower limb surgeries, it has to be used with caution for lower abdominal surgery as the spread is relatively unpredictable.
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This page is a summary of: A Comparative Study of Plain and Hyperbaric Solutions of Bupivacaine HCl During Spinal Anaesthesia, Indian Journal of Anaesthesia and Analgesia, January 2019, Red Flower Publication Private, Ltd.,
DOI: 10.21088/ijaa.2349.8471.6119.8.
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