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Hyperbaric Bupivacaine in Lower Abdominal Surgeries: A Placebo-Controlled Randomised Study
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Why is it important?
Aim: The aim of our study was to evaluate the efficacy of intrathecal fentanyl as an adjuvant to bupivacaine on the block characteristics, hemodynamic stability and side effects in patients undergoing lower abdominal surgeries. Methods: Sixty patients aged between 18-60 yrs, belonging to ASA I and II posted for elective lower abdominal surgeries under spinal anaesthesiawere recruited for the study. Patients were randomly divided into two groups of thirty each. One group received 2.5 ml of 0.5% Inj. bupivacaine with 0.5 ml of fentanyl (Group FB) and the other group received 2.5 ml of 0.5% Inj. bupivacaine with 0.5 ml of normal saline (Group B). Patients were monitored for onset, duration and quality of sensory and motor block, duration of analgesia, highest dermatomal level, hemodynamic parameters and side effects. Results: Onset of sensory block, motor block, time to reach highest dermatomal level duration of motor block was comparable between the groups. Duration of sensory block and two segment regression was prolonged in group FB compared to Group B which was statistically significant (p < 0.001). Hemodynamic stability was maintained throughout intra and post-operative period in Group FB compared to Group B. Incidence of pruritis was higher in Group FB compared to Group B which was statistically significant ( p< 0.001). Conclusion: Fentanyl as an adjuvant to bupivacaine provided sufficient post-operative analgesia with hemodynamic stability.
Perspectives
Aim: The aim of our study was to evaluate the efficacy of intrathecal fentanyl as an adjuvant to bupivacaine on the block characteristics, hemodynamic stability and side effects in patients undergoing lower abdominal surgeries. Methods: Sixty patients aged between 18-60 yrs, belonging to ASA I and II posted for elective lower abdominal surgeries under spinal anaesthesiawere recruited for the study. Patients were randomly divided into two groups of thirty each. One group received 2.5 ml of 0.5% Inj. bupivacaine with 0.5 ml of fentanyl (Group FB) and the other group received 2.5 ml of 0.5% Inj. bupivacaine with 0.5 ml of normal saline (Group B). Patients were monitored for onset, duration and quality of sensory and motor block, duration of analgesia, highest dermatomal level, hemodynamic parameters and side effects. Results: Onset of sensory block, motor block, time to reach highest dermatomal level duration of motor block was comparable between the groups. Duration of sensory block and two segment regression was prolonged in group FB compared to Group B which was statistically significant (p < 0.001). Hemodynamic stability was maintained throughout intra and post-operative period in Group FB compared to Group B. Incidence of pruritis was higher in Group FB compared to Group B which was statistically significant ( p< 0.001). Conclusion: Fentanyl as an adjuvant to bupivacaine provided sufficient post-operative analgesia with hemodynamic stability.
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This page is a summary of: Intrathecal Fentanyl as an Adjuvant to Hyperbaric Bupivacaine in Lower Abdominal Surgeries: A Placebo Controlled Randomised Study, Indian Journal of Anaesthesia and Analgesia, January 2019, Red Flower Publication Private, Ltd.,
DOI: 10.21088/ijaa.2349.8471.6119.40.
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