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Compare Efficacy of Ropivacaine and Bupivacaine for Caudal Analgesia in Paediatric Patients

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Aims and objectives: The aim of the study was to compare quality and duration of intra and post operative analgesia and need of rescue analgesia of 0.5 ml/kg of 0.25% Bupivacaine. and 0.5 ml/kg of 0.2% Ropivacaine. Methodology: We conducted a prospective, randomized, double blind study, in which 60 paediatric patients undergoing lower abdominal and genitourinary surgeries. Group A received 0.5 ml/kg of 0.25% Bupivacaine and Group B received 0.5 ml/kg of 0.2% Ropivacaine. Quality and duration of motor block, Adjunct to general anaesthesia, Margin of safety of ropivacaine over Bupivacaine was assessed. Results: Both the drugs provided post-operative analgesiaMean duration of post-operative analgesia is 344.5±29.37 min in group A & that In group B is 346.3±10.66 min (paired) two tailed p value is 0.749 which is comparable & statistically not significant. Mean duration of motor block in group A is 176.6±21.02 min and in group B was 103.8±11.79 min with P value of 0.0001 which is statistically significant. The incidence of the side effect between the two groups is not statistically significant. Conclusion: Caudal block with 0.2% Ropivacaine resulted in equal duration of analgesia with less duration of motor block as compared with 0.25% caudal Bupivacaine, without an increase in incidence of side effects when administered pre-operatively in a volume of 0.5 ml/kg to children undergoing lower abdominal and urogenital surgeries.

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Aims and objectives: The aim of the study was to compare quality and duration of intra and post operative analgesia and need of rescue analgesia of 0.5 ml/kg of 0.25% Bupivacaine. and 0.5 ml/kg of 0.2% Ropivacaine. Methodology: We conducted a prospective, randomized, double blind study, in which 60 paediatric patients undergoing lower abdominal and genitourinary surgeries. Group A received 0.5 ml/kg of 0.25% Bupivacaine and Group B received 0.5 ml/kg of 0.2% Ropivacaine. Quality and duration of motor block, Adjunct to general anaesthesia, Margin of safety of ropivacaine over Bupivacaine was assessed. Results: Both the drugs provided post-operative analgesiaMean duration of post-operative analgesia is 344.5±29.37 min in group A & that In group B is 346.3±10.66 min (paired) two tailed p value is 0.749 which is comparable & statistically not significant. Mean duration of motor block in group A is 176.6±21.02 min and in group B was 103.8±11.79 min with P value of 0.0001 which is statistically significant. The incidence of the side effect between the two groups is not statistically significant. Conclusion: Caudal block with 0.2% Ropivacaine resulted in equal duration of analgesia with less duration of motor block as compared with 0.25% caudal Bupivacaine, without an increase in incidence of side effects when administered pre-operatively in a volume of 0.5 ml/kg to children undergoing lower abdominal and urogenital surgeries.

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This page is a summary of: To Study and Compare Efficacy of Ropivacaine and Bupivacaine for Caudal Analgesia in Paediatric Patients, Indian Journal of Anaesthesia and Analgesia, January 2019, Red Flower Publication Private, Ltd.,
DOI: 10.21088/ijaa.2349.8471.6119.28.
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