What is it about?
Fentanyl 2 mcg/ ml and evobupivacaine 0.125% Alone for Postoperative Pain Management
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Why is it important?
Introduction: The aim of the study was to compare effectiveness of single dose epidural 0.125% levobupivacaine with fentanyl 2 mcg/ml and 0.125% levobupivacaine alone in patients undergoing elective lower limb orthopaedic surgery. Methodology: We designed a prospective, randomized, double blind study, in which 60 patients with ASA1 and ASA2 were scheduled to undergo elective lower limb orthopedic surgery. Group A received single epidural block with 8 ml of 0.125% levobupivacaine and Group B received epidural block with 8 ml of 0.125% levobupivacaine and 2 mcg/ml fentanyl. Duration of analgesia, Quality of analgesia, Degree of motor blockade, sedation score, hemodynamic changes and side effects were assessed. Results: Duration of postoperative analgesia for group B (366±39.70 min) was longer as compared to group A (236±34.99 min). Quality of anaesthesia was significantly better in group B as compared Group A. Conclusion: We conclude that addition of fentanyl 2 mcg/ml to epidural 0.125% levobupivacaine produces significantly better quality and longer duration of postoperative analgesia, good hemodynamic stability and no side effect as compared to 0.125% levobupivacainealone in patient undergoing elective lower limb orthopedic surgeries.
Perspectives
Introduction: The aim of the study was to compare effectiveness of single dose epidural 0.125% levobupivacaine with fentanyl 2 mcg/ml and 0.125% levobupivacaine alone in patients undergoing elective lower limb orthopaedic surgery. Methodology: We designed a prospective, randomized, double blind study, in which 60 patients with ASA1 and ASA2 were scheduled to undergo elective lower limb orthopedic surgery. Group A received single epidural block with 8 ml of 0.125% levobupivacaine and Group B received epidural block with 8 ml of 0.125% levobupivacaine and 2 mcg/ml fentanyl. Duration of analgesia, Quality of analgesia, Degree of motor blockade, sedation score, hemodynamic changes and side effects were assessed. Results: Duration of postoperative analgesia for group B (366±39.70 min) was longer as compared to group A (236±34.99 min). Quality of anaesthesia was significantly better in group B as compared Group A. Conclusion: We conclude that addition of fentanyl 2 mcg/ml to epidural 0.125% levobupivacaine produces significantly better quality and longer duration of postoperative analgesia, good hemodynamic stability and no side effect as compared to 0.125% levobupivacainealone in patient undergoing elective lower limb orthopedic surgeries.
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This page is a summary of: Comparison of Epidural Levobupivacaine 0.125% with Fentanyl 2 mcg/ ml and evobupivacaine 0.125% Alone for Postoperative Pain Management, Indian Journal of Anaesthesia and Analgesia, January 2019, Red Flower Publication Private, Ltd.,
DOI: 10.21088/ijaa.2349.8471.6119.2.
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