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Conditions at 60 Seconds with Different Doses of Rocuronium Using the Train of Four Monitoring

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Objective: To evaluate the intubating conditions with rocuronium at. 6mg/kg (2*ED95) and 0.9mg/kg (3*ED95) at 60 seconds using the timing principle. Methods: 60 patients were divided into 2 groups of 30 each. Group A received 0.9mg/kg and group B received 0.6mg/kg of rocuronium. Intubation was done at 60 s. The Train of four monitoring was done at the adductor pollicis muscle. The TOF count at intubation and time to loss of TOF were noted and compared. Results: Intubating conditions were excellent 13 (65%) in group A compared to 9 (45%) in group B and was statistically significant. The TOF count at intubation was not statistically significant (p=0.677) between the groups where as time to loss of TOF (p=0.03) were significant between the groups. Conclusion: Intubating conditions were better in group A in comparision with group B but both the groups provided clinically acceptable conditions for intubation. The use of train of four count at the adductor pollicis as a guide for laryngeal muscle paralysis is questionable.

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Objective: To evaluate the intubating conditions with rocuronium at. 6mg/kg (2*ED95) and 0.9mg/kg (3*ED95) at 60 seconds using the timing principle. Methods: 60 patients were divided into 2 groups of 30 each. Group A received 0.9mg/kg and group B received 0.6mg/kg of rocuronium. Intubation was done at 60 s. The Train of four monitoring was done at the adductor pollicis muscle. The TOF count at intubation and time to loss of TOF were noted and compared. Results: Intubating conditions were excellent 13 (65%) in group A compared to 9 (45%) in group B and was statistically significant. The TOF count at intubation was not statistically significant (p=0.677) between the groups where as time to loss of TOF (p=0.03) were significant between the groups. Conclusion: Intubating conditions were better in group A in comparision with group B but both the groups provided clinically acceptable conditions for intubation. The use of train of four count at the adductor pollicis as a guide for laryngeal muscle paralysis is questionable.

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This page is a summary of: Comparision of Intubating Conditions at 60 Seconds with Different Doses of Rocuronium Using the Train of Four Monitoring, Indian Journal of Anaesthesia and Analgesia, January 2018, Red Flower Publication Private, Ltd.,
DOI: 10.21088/ijaa.2349.8471.5618.5.
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