What is it about?
Fentanyl as Adjuvant on Hemodynamic Changes in Lower Abdominal and Lower Limb Surgeries
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Why is it important?
Background: In regional anaesthesia and analgesia, maintaining better hemodynamic stability and minimal side effects is very much essential. A number of adjuvants have been combined with local anaesthesia’s (LA) to improve the effectiveness of LA. Therefore, in the present study, the efficacy of Bupivacaine with dexmedetomidine or Fentanyl as adjuvant in maintaining better hemodynamic stability was studied. Materials and Methods: 60 patients of ASA group-I and II aged between 18-60 years undergoing elective lower abdominal, urologic, lower limb surgeries were selected and divided into two groups of 30 each. Group “BP” received intrathecally 12.5mg 0.5% of Bupivacaine +5 µg of dexmeditomidine while group “BF” received 0.5% Bupivacaine +12.5µg of Fentanyl. Result: Group-BD and in Group-BF did not differ significantly (p>0.05) with respect to heart rate, SBP and DBP at any interval of time. There was an insignificant variation in the side effects of anaesthesia.VAS was 0.03± 0.18 in group BD and 0.10 ± 0.31 in group BF, which was statistically in- significant. Whereas, VAS of patients anesthetized by Bupivacaine with Dexmeditomedine or Fentanyl as adjuvantwas statistically significant at 3 hours and 12 hours (p<0.05). Conclusion: Bupivacaine with dexmeditomidine provided good quality of intraoperative analgesia with minimal side effectsandbetter hemodynamic stability.
Perspectives
Background: In regional anaesthesia and analgesia, maintaining better hemodynamic stability and minimal side effects is very much essential. A number of adjuvants have been combined with local anaesthesia’s (LA) to improve the effectiveness of LA. Therefore, in the present study, the efficacy of Bupivacaine with dexmedetomidine or Fentanyl as adjuvant in maintaining better hemodynamic stability was studied. Materials and Methods: 60 patients of ASA group-I and II aged between 18-60 years undergoing elective lower abdominal, urologic, lower limb surgeries were selected and divided into two groups of 30 each. Group “BP” received intrathecally 12.5mg 0.5% of Bupivacaine +5 µg of dexmeditomidine while group “BF” received 0.5% Bupivacaine +12.5µg of Fentanyl. Result: Group-BD and in Group-BF did not differ significantly (p>0.05) with respect to heart rate, SBP and DBP at any interval of time. There was an insignificant variation in the side effects of anaesthesia.VAS was 0.03± 0.18 in group BD and 0.10 ± 0.31 in group BF, which was statistically in- significant. Whereas, VAS of patients anesthetized by Bupivacaine with Dexmeditomedine or Fentanyl as adjuvantwas statistically significant at 3 hours and 12 hours (p<0.05). Conclusion: Bupivacaine with dexmeditomidine provided good quality of intraoperative analgesia with minimal side effectsandbetter hemodynamic stability.
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This page is a summary of: Comparative Study of Efficacy of Bupivacaine with Dexmeditomidine and Fentanyl as Adjuvant on Hemodynamic Changes in Lower Abdominal and Lower Limb Surgeries, Indian Journal of Anaesthesia and Analgesia, January 2018, Red Flower Publication Private, Ltd.,
DOI: 10.21088/ijaa.2349.8471.5218.8.
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