What is it about?
Adjuvant to Local Anesthetic in Lower Abdominal Surgeries: A Randomized Control Clinical Trail
Featured Image
Photo by Nappy on Unsplash
Why is it important?
Introduction: Management of both intraoperative anaesthesia and post operative pain by neuraxial block demands addition of additives which gives good and prolonged postoperative analgesia with minimal side effects. Among various choices of additives, alpha 2 agonists are one among the preferred drugs. Aim of the Study: To compare the efficacy of a mixture of 0.5% bupivacaine and clonidine 150 micrograms with 0.5% bupivacaine used alone in lumbar epidural anaesthesia for lower abdominal surgeries. Materials and Methods: Fifty patients belonging to ASA I or ASA II category were selected for the study. All patients were randomly divided into two groups of 25 each. Group I, the control group received 10-15 ml 0.5%of bupivacaine and 1 ml of normal saline and Group II. Clonidine group received 10-15 ml of 0.5% bupivacaine and 150µgm of clonidine. Onset and duration of sensory and motor block and duration of post-operative analgesia along with adverse effect were studied. Statistical analysis was performed using student unpaired t –test and chi- square test. Results: Epidural clonidine in the dose of 150 µgm combined with 0.5% bupivacaine produced an effective anaesthesia with rapid onset, intensified and prolong blockade and an extended duration of post operative analgesia with minimum side effects.
Perspectives
Introduction: Management of both intraoperative anaesthesia and post operative pain by neuraxial block demands addition of additives which gives good and prolonged postoperative analgesia with minimal side effects. Among various choices of additives, alpha 2 agonists are one among the preferred drugs. Aim of the Study: To compare the efficacy of a mixture of 0.5% bupivacaine and clonidine 150 micrograms with 0.5% bupivacaine used alone in lumbar epidural anaesthesia for lower abdominal surgeries. Materials and Methods: Fifty patients belonging to ASA I or ASA II category were selected for the study. All patients were randomly divided into two groups of 25 each. Group I, the control group received 10-15 ml 0.5%of bupivacaine and 1 ml of normal saline and Group II. Clonidine group received 10-15 ml of 0.5% bupivacaine and 150µgm of clonidine. Onset and duration of sensory and motor block and duration of post-operative analgesia along with adverse effect were studied. Statistical analysis was performed using student unpaired t –test and chi- square test. Results: Epidural clonidine in the dose of 150 µgm combined with 0.5% bupivacaine produced an effective anaesthesia with rapid onset, intensified and prolong blockade and an extended duration of post operative analgesia with minimum side effects.
Red Flower Publication Publications
Red Flower Publication Pvt Ltd
Read the Original
This page is a summary of: Efficacy of Epidural Clonidine as an Adjuvant to Local Anesthetic in Lower Abdominal Surgeries: A Randomized Control Clinical Trail, Indian Journal of Anaesthesia and Analgesia, January 2018, Red Flower Publication Private, Ltd.,
DOI: 10.21088/ijaa.2349.8471.5218.18.
You can read the full text:
Contributors
The following have contributed to this page
