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Placenta and Foetus in Different Grades of Toxemia of Pregnacy and Normotensive Pregnant Women

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Why is it important?

The placenta is a unique organ, short-lived by design. Its existence is vital for the persistence of human embryo/foetus in the intrauterine environment. Structural and functional derangement of placenta arouses a considerable interest, as this may be the only index to measure the adequacy of the foetal environment. Hypertensive disorders generating complications during pregnancy (Toxaemia of pregnancy) which are common and forming deadly characters along with haemorrhage and infection. Maternal hypertension (toxaemia of pregnancy) is diagnosed in 6–10% of all deliveries which is related with 22% of perinatal foetal deaths and 30% of maternal death. The present study has done in 240 pregnant mothers, divided into four groups 40 cases of mild preeclampsia, 40 cases of severe preeclampsia, 40 cases of Eclampsia, 120 cases of control (Normotensive) pregnant women admitted in Department of Obs and gynaecology, Rama medical college, Hospital and research centre, Mandana, Kanpur (Up) and Shadan institute of medical sciences, Peeranchuruvu, Hyderabad, Telangana (India). The placentae were weighed with a standard weighing machine. The fetal weight was noted from the case records provided. In this present study the mean placental, birth weights were low in different grades of toxaemia of pregnancy when compared with the control group. The fetoplacental weight ratio was higher in cases of eclampsia, severe and mild preeclampsia when compared with the control group.

Perspectives

The placenta is a unique organ, short-lived by design. Its existence is vital for the persistence of human embryo/foetus in the intrauterine environment. Structural and functional derangement of placenta arouses a considerable interest, as this may be the only index to measure the adequacy of the foetal environment. Hypertensive disorders generating complications during pregnancy (Toxaemia of pregnancy) which are common and forming deadly characters along with haemorrhage and infection. Maternal hypertension (toxaemia of pregnancy) is diagnosed in 6–10% of all deliveries which is related with 22% of perinatal foetal deaths and 30% of maternal death. The present study has done in 240 pregnant mothers, divided into four groups 40 cases of mild preeclampsia, 40 cases of severe preeclampsia, 40 cases of Eclampsia, 120 cases of control (Normotensive) pregnant women admitted in Department of Obs and gynaecology, Rama medical college, Hospital and research centre, Mandana, Kanpur (Up) and Shadan institute of medical sciences, Peeranchuruvu, Hyderabad, Telangana (India). The placentae were weighed with a standard weighing machine. The fetal weight was noted from the case records provided. In this present study the mean placental, birth weights were low in different grades of toxaemia of pregnancy when compared with the control group. The fetoplacental weight ratio was higher in cases of eclampsia, severe and mild preeclampsia when compared with the control group.

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This page is a summary of: A Comparative Study to Evaluate The Morphometry of Placenta and Foetus in Different Grades of Toxemia of Pregnacy and Normotensive Pregnant Women, Indian Journal of Anatomy, July 2020, Red Flower Publication Private, Ltd.,
DOI: 10.21088/ija.2320.0022.9320.7.
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