Activity of Extract Homalomena Occulta Rhizome in Inhibiting Kidney Stone Formation in Rats

What is it about?

Homalomena occulta is a plant that grows in Madiun, especially Caruban. Patients can overcome kidney stone disease by boiling the H. occulta (nampu) rhizome with water. The present study aimed to evaluate the antilithiatic effect of the ethanol extract of the H. occulta rhizome in preventing nephrolithiasis in rats. Ethylene glycol was used to induce the urolithiasis in the Wistar rats. In the study of the activity of inhibiting kidney stone formation from the ethanolic extract of nampu rhizome (Homalomena occulta), induced by ethylene glycol with parameters of kidney ratio and calcium content using the AAS (Absorbtion Atomic Spectroscopy) method, it can be concluded that: 250 mg and 500 mg can inhibit the formation of kidney stones but 1000 mg could not inhibit the formation of kidney stones in ethyleneglycol-induced wistar rats.

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Why is it important?

Nampu or occulta is a plant that based on the empirical experience of the Madiun people can shed kidney stones so that the plant is used as an alternative treatment for kidney stones.

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