What is it about?
Causal inference, which can inform potential treatment targets, is important in medical research. Mendelian randomization investigation is a tool for performing causal analysis using genetics. This primer explains the basic concepts of Mendelian randomization investigation with examples and opportunities in nephrology.
Featured Image
Why is it important?
Due to the increased availability of genetic data, there has been a surge in the publication of Mendelian randomization studies. This primer enhances the reader's ability to interpret Mendelian randomization studies and identify opportunities for the application of Mendelian randomization analysis in nephrology.
Perspectives
It has been a great pleasure to coauthor this primer with Dr. Kottgen. We tried to summarize the basics and make technical concepts more accessible to the general reader.
Adrienne Tin
University of Mississippi Medical Center
Read the Original
This page is a summary of: Mendelian Randomization Analysis as a Tool to Gain Insights into Causes of Diseases: A Primer, Journal of the American Society of Nephrology, June 2021, American Society of Nephrology,
DOI: 10.1681/asn.2020121760.
You can read the full text:
Contributors
The following have contributed to this page
