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There are multiple unmet needs in kidney transplantation and therapeutic stagnation has occurred. More recently, there is renewed interest in kidney transplantation, focusing on mitigating both cellular and antibody mediated rejection, along with novel interventions. Endpoints in trials are discussed, recognizing that the context of use as well as mechanism of a specific agent class are important. Such new endpoints will encourage the development of therapies that will improve long-term graft survival.

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This page is a summary of: Poised for Innovation, Journal of the American Society of Nephrology, August 2024, Wolters Kluwer Health,
DOI: 10.1681/asn.0000000000000475.
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