Ketogenic Diet for Nephropathic Cystinosis

What is it about?

Ketogenic diet is a low-carbohydrate, high-fat eating plan that has gained popularity for weight loss and health benefits. The study in animal models of cystinosis has provided intriguing insights into the potential benefits of a ketogenic diet in mitigating kidney-related symptoms of Fanconi syndrome such as proteinuria, glycosuria, and polyuria. Moreover, the diet seemed to contribute to healthier kidney function, as evidenced by the reduction in interstitial cell infiltration, fibrosis, and apoptosis.

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Photo by Brooke Lark on Unsplash

Photo by Brooke Lark on Unsplash

Why is it important?

The reduction in symptoms and the preservation of kidney structure are promising indicators of the diet's therapeutic potential. This could be a stepping stone towards new dietary guidelines for managing similar conditions in humans.