What is it about?

He here describe a very sensitive technique for BRAF testing in melanoma.

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Why is it important?

This is of great importance given the fact that these BRAF V600- results have a direct impact on the choice of treatment (and therefore survival) in metastatic melanoma patients. Furthermore, rare genetic alterations such as BRAF fusions can respond to sorafenib.

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This page is a summary of: Hybrid Capture‐Based Genomic Profiling Identifies BRAF V600 and Non‐V600 Alterations in Melanoma Samples Negative by Prior Testing, The Oncologist, January 2019, Alphamed Press,
DOI: 10.1634/theoncologist.2018-0271.
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