What is it about?
The aim of this study was to evaluate the association between insulin resistance and thyroid pathology in obese patients, and compare the results between insulin-resistant and noninsulin-resistant patients.
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Why is it important?
The present study aimed at assessing the relationship between IR and pathologies of the thyroid by performing a morphofunctional thyroid evaluation of a representative sample of obese patients. A secondary objective was to analyze the differences between obese patients with and without IR. We also investigated the association between morning serum cortisol, thyroid function, and IR.
Perspectives
obese patients displayed a significantly positive correlation between HOMA-IR values and TSH levels. Our findings validate the cutoff value of 2.5 for HOMA-IR in regards to TSH levels, which was higher in obese patients with IR when compared with those without IR. Although serum cortisol correlated with HOMA-IR values and serum TSH levels, the correlation of HOMA-IR and TSH remained even after adjusting the cortisol's influence.
PhD, MD racataianu nicoleta
UMF Iuliu Hatieganu Cluj-Napoca Romania
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This page is a summary of: Thyroid disorders in obese patients. Does insulin resistance make a difference?, Archives of Endocrinology and Metabolism, December 2017, Archives of Endocrinology and Metabolism,
DOI: 10.1590/2359-3997000000306.
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