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Impaired progesterone (P4) signaling is linked to endometrial dysfunction and infertility in women with polycystic ovary syndrome (PCOS). Our study is the first to show that the therapeutic effects of metformin on the regulation of uterine function in PCOS-like rats is mediated through P4 signaling.

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This page is a summary of: Uterine progesterone signaling is a target for metformin therapy in PCOS-like rats, Journal of Endocrinology, March 2018, Bioscientifica,
DOI: 10.1530/joe-18-0086.
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