Not one event, but a series of events required for pregnancy establishment

What is it about?

Pregnancy is unique event, but rather than new gene generations, mammals mostly use those found in non-placental animals. This paper describes that molecules required for lymphocyte homing and those required for cancer metastasis are all functioning during the period of conceptus implantation and placentation. Perhaps more importantly, timing and degree of various gene expression in different cell types are controlled.

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Why is it important?

Our finding show that gene expression and their cell developments are sequencially and continuously coordinated for successful establishment of pregnancy.

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