Thyroid hormones induce browning of white fat

What is it about?

It has been known for more than a century that thyroid hormones (THs) increase the basal metabolic rate. We show for the first time that THs, by acting in the hypothalamus, regulate the conversion of white fat to beige fat, a process that it is known to increase metabolic rate. Of note, we provide association of circulating THs and browning in humans, which indicates that this mechanism may be relevant in humans.

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