What is it about?
Metformin is a widely used antidiabetic drug and it is capable of inducing MALA (Metformin Associated Lactic Acidosis) in higher plasma concentrations.
Featured Image
Why is it important?
Metformin is a cationic drug and it depends the transporters like OCTs and MATEs of renal cells for it's elimination. Concomitant use of Metformin with the drugs inhibiting MATEs and OCTs may result in elevated plasma concentrations of Metformin and increased risk of MALA.
Perspectives
I hope this article would be useful to the millions of Metformin Users to avoid the incidence of Lactic acidosis.
Dr Naina Mohamed Pakkir Maideen
Dubai Health Authority
Read the Original
This page is a summary of: Drug Interactions of Metformin Involving Drug Transporter Proteins, Advanced Pharmaceutical Bulletin, December 2017, International Society for Phytocosmetic Scicences,
DOI: 10.15171/apb.2017.062.
You can read the full text:
Contributors
The following have contributed to this page
