What is it about?
The reaction of 5(4H)-oxazolones with tetraethyl methanediylbis(phosphonate) afforded new 1,1-bisphosphonate and 1,1-bisphosphonic acid derivatives. Moreover, 5(4H)-oxazolones reacted with Wittig reagents to give the corresponding heterocyclic products.
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Why is it important?
The reaction of the oxazole system with bisphosphonates and Wittig reagent to give new compounds tested as Anticancer and Antischistosomal Activity.
Perspectives
This article find an easy way for the synthesis of New Bisphosphonate and Bisphosphonic Acid Derivatives,
Professor Dr. AMIN Farouk FAHMY
Ain Shams University ,Egypt
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This page is a summary of: Synthesis of New Bisphosphonate and Bisphosphonic Acid Derivatives and Heterocyclic and Dialkylcarbamoyl Oxazolone Derivatives with Anticancer and Antischistosomal Activity, Zeitschrift für Naturforschung B, January 2011, De Gruyter,
DOI: 10.1515/znb-2011-1011.
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