Evaluation of biological variations in glucose and glycated hemoglobin levels in healthy individuals

What is it about?

The initial goal was to estimate BVD for both analytes in detail based on the guidance of relevant organizations and experts. The other goal was to guide to the clinician to make decision about reference interval or RCV should be used for both analytes while managing the DM procedere.

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Why is it important?

We thought that guidelines from relevant international organizations should be followed to standardize the study design and appropriately calculate BVCs for any analyte in BV studies. Finally, reference change value should be used to evaluate meaningful differences in HbA1c levels instead of the reference interval.

Perspectives