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Two different approaches are available to design laboratory QC procedures - the traditional Total Error model and the new metrology/traceability model. Performance can be assessed based on theoretical rejection characteristics or by alternatively by empirical simulations of error conditions.

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This page is a summary of: How to evaluate fixed clinical QC limits vs. risk-based SQC strategies, Clinical Chemistry and Laboratory Medicine (CCLM), June 2022, De Gruyter,
DOI: 10.1515/cclm-2022-0539.
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