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As a novel biomarker for predicting AKI, [TIMP-2]•[IGFBP7] has already proved its validity and accuracy in multiple studies in many fields and has been applied by the FDA for clinical application. Further studies regarding the application value of [TIMP-2]•[IGFBP7] in different clinical contexts, different patient populations, different disease spectrum, are needed.

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This page is a summary of: Current understanding and future directions in the application of TIMP-2 and IGFBP7 in AKI clinical practice, Clinical Chemistry and Laboratory Medicine (CCLM), April 2019, De Gruyter,
DOI: 10.1515/cclm-2018-0776.
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