What is it about?

Lipoprotein-associated phospholipase A2 (Lp-PLA2), also known as plasma platelet activating factor acetylhydrolase (PAF-AH), is a Ca2+-independent enzyme implicated in inflammation and atherosclerosis,

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Why is it important?

The determination of Lp-PLA2 levels may aid in the identification of individuals at high risk for coronary heart disease, even in Children.

Perspectives

This study is the first one to compare Lp-PLA2 mass between obese and control children in such a young age group.

Dr Ioannis Papassotiriou
Aghia Sophia Children's Hospital, Athens, Greece

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This page is a summary of: Elevated circulating levels of lipoprotein-associated phospholipase A2 in obese children, Clinical Chemistry and Laboratory Medicine (CCLM), January 2015, De Gruyter,
DOI: 10.1515/cclm-2014-1081.
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