What is it about?
Amyloid-beta is a protein that found in cerebrospinal fluid that is measured to test for Alzheimer’s disease. Unfortunately, this protein can be difficult to measure as it sticks to surfaces (like plastic test tubes) and other molecules. We carefully optimized the approach for measuring amyloid-beta, resulting in a testing process with improved accuracy for measuring the protein under a variety of conditions.
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Why is it important?
Amyloid-beta protein is the key diagnostic biomarker for Alzheimer's disease. Accurately measuring this protein is critical to accurately diagnosing Alzheimer's disease.
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This page is a summary of: Establishing pre-analytical requirements and maximizing peptide recovery in the analytical phase for mass spectrometric quantification of amyloid-β peptides 1–42 and 1–40 in CSF, Clinical Chemistry and Laboratory Medicine (CCLM), December 2021, De Gruyter,
DOI: 10.1515/cclm-2021-0549.
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