What is it about?
The HCC incidence rate among patients with cirrhosis has been shown to be 2-4% per year. Improvement in survival rate could be achieved through implementation of early detection and curative treatment of HCC, so it is necessary to carry out the routine surveillance for HCC in cirrhotic patients
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Why is it important?
It is premature to abandon the current process of HCC surveillance, though these results have confirmed the inadequacies of current HCC surveillance strategies. Clinical practices have realized the low compliance to the repeated screening, unnecessary follow-up procedures, and anxiety in the patients with cirrhosis.
Perspectives
In addition to monitoring regular protein biomarkers, detection of the genetic alterations in circulating tumor DNA in peripheral blood of the at-risk individuals showed promise for finding curable HCC. With the discovery of new monitoring indicators, a better modality of HCC surveillance to further improve survival is needed.
Xiangjun Qian
Read the Original
This page is a summary of: Hepatocellular Carcinoma Surveillance and Treatment: A Way to Reduce Cancer-related Mortality in Cirrhotic Patients, Journal of Clinical and Translational Hepatology, March 2019, Xia & He Publishing,
DOI: 10.14218/jcth.2019.00002.
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