What is it about?
This study looked at ESBL-producing Klebsiella isolates from hospitals in Japan. We used a tool called Klebsiella MALDI TypeR to identify the bacteria species and performed PCR tests to detect genes that code for β-lactamase enzymes. These enzymes help bacteria break down antibiotics and resist their effects. The study looked at how Klebsiella isolates resist different antibiotics and the rate of AmpC enzyme production.
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Photo by Volodymyr Hryshchenko on Unsplash
Why is it important?
Klebsiella bacteria are becoming resistant to many antibiotics, making infections harder to treat. There is not much data on ESBL-producing Klebsiella in Japan, so this study fills a critical knowledge gap. The findings help us understand how to treat infections and why we need to keep monitoring and researching to fight antibiotic resistance.
Perspectives
This research helped us understand more about ESBL-producing Klebsiella in Japan. The most common group is the CTX-M-1, which is resistant to many antibiotics. This information is important for changing how we treat infections caused by these bacteria.
Dr Naoki Watanabe
Kameda Medical Center
Read the Original
This page is a summary of: Antimicrobial resistance and AmpC production in ESBL-producing Klebsiella pneumoniae and Klebsiella quasipneumoniae: A retrospective study in Japanese clinical isolates, PLoS ONE, May 2024, PLOS,
DOI: 10.1371/journal.pone.0303353.
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