What is it about?
Understanding the motion of migratory cells is fundamental in many areas i.e. cancer metastasis. Main driver of cell motion is the cytoskeleton. We developed an open-source software with easy-to-use graphical user interface to aid researchers in tracking and analysing cytoskeletal fibers in bulk and as single objects over time.
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Photo by Alina Grubnyak on Unsplash
Why is it important?
Cytoskeletal composition is often analysed for single points in time or in fixed cells. Following the whole network over time and trackingn all individual parts will give deeper understanding between morphology and cell behavior.
Perspectives
We need to develop open-source tools to aid fellow researchers in their work.
Lara Hauke
University Medical Center Göttingen
Read the Original
This page is a summary of: FilamentSensor 2.0: An open-source modular toolbox for 2D/3D cytoskeletal filament tracking, PLoS ONE, February 2023, PLOS,
DOI: 10.1371/journal.pone.0279336.
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