What is it about?
The study is about the immune response and processes incurred by surgery. We have observed that they are similar in Both normal healing and rejection at the beginning. and later on the immune system shifts towards rejection of what it identifies as non self.
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Why is it important?
Studies such as this are important for the field of allotransplantation (transplantation from another donor) to identify the different mechanisms at play and possible targets for immune modulation and interventions.
Perspectives
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This page is a summary of: Immunological and inflammatory mapping of vascularized composite allograft rejection processes in a rat model, PLoS ONE, July 2017, PLOS,
DOI: 10.1371/journal.pone.0181507.
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