What is it about?
rev-erb alpha and the circadian clock controls hepatic de novo lipogenesis and bile acid synthesis by modulating SREBP and LXR signaling
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Why is it important?
shows for the first time that circadian clock and lipid and bile homeostasis are co regulated by a single recpetor rev-erb alpha
Perspectives
rev-erb alpha modulators in liver could be used to fight fatty liver
thierry claudel
Medical University of Vienna
Read the Original
This page is a summary of: REV-ERBα Participates in Circadian SREBP Signaling and Bile Acid Homeostasis, PLoS Biology, September 2009, PLOS,
DOI: 10.1371/journal.pbio.1000181.
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