What is it about?
Numerous studies have demonstrated that acute kidney injury(AKI)in children increases the risk of poor outcomes. We conducted a record review at the pediatric kidney unit at the University Teaching Hospital in Zambia covering the period 2017 to 2021. Close to a third of all cases seen by the unit had AKI and 60% of all the AKI cases were caused by malaria. Three-quaters of the children with AKI received dialysis with 80% of these undergoing peritoneal dialysis. Close to half of children receiving peritoneal dialysis utilized improvised catheters. A fifth of the children developed chronic kidney disease and 5.6% died.Over three- quaters of all AKI patients were lost to follow up at one year post discharge
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Why is it important?
This study provides information on the major conditions leading to dialysis in a Zambian population. The study includes a large group of children with severe AKI (KDIGO stage 3) caused by malaria. The data also shows that improvised PD catheters can save lives in contexts where alternatives are not readily available .
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This page is a summary of: Malaria is the leading cause of acute kidney injury among a Zambian paediatric renal service cohort retrospectively evaluated for aetiologies, predictors of the need for dialysis, and outcomes, PLoS ONE, October 2023, PLOS,
DOI: 10.1371/journal.pone.0293037.
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