What is it about?
Like a pacemaker for the heart, nerve stimulation devices are implanted in the body and programmed to send targeted pulses of electricity into nerves. These electrical pulses can initiate or suppress signals in the nerve, changing the regulation of organ functions to treat disease. Nerve stimulation is a promising alternative to drugs, but, like drugs, requires determination of the effective dose. This article describes an open-source software platform that automates modeling of electrical stimulation of nerves. The system can be used to determine the effect of the electrical dose on nerve stimulation.
Featured Image
Photo by Robina Weermeijer on Unsplash
Why is it important?
The open-source platform allows users to predict how specific nerves respond to different parameters of electrical stimulation. The platform allows simple creation of accurate models of new electrical stimulation therapies for a variety of diseases, including diabetes, rheumatoid arthritis, and cardiovascular disease.
Perspectives
Read the Original
This page is a summary of: ASCENT (Automated Simulations to Characterize Electrical Nerve Thresholds): A pipeline for sample-specific computational modeling of electrical stimulation of peripheral nerves, PLoS Computational Biology, September 2021, PLOS,
DOI: 10.1371/journal.pcbi.1009285.
You can read the full text:
Resources
Contributors
The following have contributed to this page