A REVIEW ON QUORUM SENSING INHIBITORS

What is it about?

Antibiotic is the powerful invention of science to damage bacterial infections. But nowadays, use of careless increasing doses of this antibiotic has led to increase the resistant power of enemy bacteria. Bacteria are caused many infectious diseases by proliferation within quorum sensing (QS) mediated biofilms. Quorum sensing can develop microbial pathogenic traits including biofilm formation. Try to smash biofilms have led the identification of bioactive molecules evolved by prokaryotes and eukaryotes. The activity of these bioactive molecules, are basically done by quenching the QS systems. For this reason, we need to inhibit quorum sensing, which may be done by various types of inhibitors called quorum sensing inhibitors (QSI). Synthetic and natural QSIs play the vital role to inhibit QS. In this review, some examples of QS inhibitors like synthetic and natural based QS inhibitors are highlighted. This review is also focused on the inhibition of QS mechanisms and the application of QSI in various fields.

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Photo by Raimond Klavins on Unsplash

Photo by Raimond Klavins on Unsplash