Anticancer effects of the bioactive peptide Lunasin

What is it about?

Lunasin has been found to have both chemopreventive and therapeutic activity against a variety of cancer types. Recent studies have indicated that Lunasin may also activate innate immunity, which may contribute to its anticancer activities. Previous mouse studies have used mice with immune system deficits. The purpose of these studies was to establish mouse models for melanoma and lung cancer that used mice with a fully competent immune system.

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Why is it important?

These results validate that these two models can be used to study the effects of Lunasin on the immune system and how these effects impact Lunasin's anticancer activity. This is important given the current clinical focus on cancer immunotherapies and the search for compounds that can enhance immune responses to treat cancer.