What is it about?
This is a study of blood pressure in patients with childhood-onset lupus. Lupus is a common autoimmune disease that can be diagnosed in childhood.
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Why is it important?
Blood pressure is elevated in hypertension and can increase an individual's risk for cardiovascular diseases, such as heart attack and stroke. Having lupus also increases your risk for developing cardiovascular disease. It is not clear whether physicians should manage BP or hypertension differently in patients with lupus.
Perspectives
Ambulatory BP monitoring is the gold standard for measuring a person's blood pressure. There is not a lot of data about ambulatory BP monitoring in patients with lupus. There is even less information available on how to manage patients with childhood-onset lupus. This publication suggests that nocturnal BP elevations, or at least a failure of BP to dip to lower levels at night, is a common occurrence in children with lupus. Future studies should incorporate ambulatory BP monitoring in order to study the role of nocturnal hypertension and attenuated BP dipping on cardiovascular disease risk in lupus.
Dr Scott E Wenderfer
Baylor College of Medicine
Read the Original
This page is a summary of: Nocturnal Hypertension and Attenuated Nocturnal Blood Pressure Dipping is Common in Pediatric Lupus, F1000Research, June 2015, Faculty of 1000, Ltd.,
DOI: 10.12688/f1000research.6532.1.
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