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HBD-3 and LL-37 are for the first time shown to be significantly upregulated in Kaposi’s sarcoma skin lesions as compared with skin of healthy controls. The obtained data suggest a possible contribution of HBD-3 and LL-37 in the innate and adaptive immune response target against HHV-8. Another possibility is the potential involvement of these antimicrobial peptides in the pathogenesis of KS.
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This page is a summary of: Upregulation of human β-defensin-3 and cathelicidin LL-37 in Kaposi’s sarcoma, F1000Research, October 2012, F1000Research,
DOI: 10.12688/f1000research.1-38.v1.
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