Evaluation of endothelial dysfunction and its improvement after cardiac rehabilitation

What is it about?

Endothelial function is considered an independent predictor for risk of future cardiovascular events in cardiovascular and noncardiovascular patients. Given the prevalence of cardiovascular disease (CVD), preclinical detection may help modify atherosclerosis and prevent events. Although traditional cardiovascular risk factors relate to future CVD, the predictive value of these risk factors can be relatively limited. Contemporary scientific attention has focused on alternative direct measures of arterial function . Studies have provided unique insights into the pathophysiology of disease processes, the response to treatment and prognostic information that may be helpful in risk prediction.

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Why is it important?

The endothelium plays an important role in maintaining vascular homeostasis and regulating blood vessel function. Endothelial function is considered an independent predictor for risk of future cardiovascular events in cardiovascular and noncardiovascular patients[1]. Given the prevalence of cardiovascular disease (CVD), early detection is crucial. Although traditional cardiovascular risk factors relate to future CVD, the predictive value of these risk factors can be relatively limited. Contemporary scientific attention has focused on alternative direct measures of arterial function[2]. Cardiac rehabilitation (CR) is critically important in secondary prevention of cardiovascular disease. CR has been reported to be negatively correlated with reinfarction, cardiac morbidity and all-cause mortality.

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