The original clinical description of familial isolated pituitary adenomas (FIPA)

What is it about?

This study described for the first time in the peer-reviewed literature a condition called FIPA: familial isolated pituitary adenomas. FIPA is a disease in which pituitary adenomas occur in various affected members in the absence of other diseases such as MEN1. FIPA expanded the definition of how familial pituitary adenomas could occur and includes all clinical types: acromegaly, prolactinoma, non-functioning adenomas, Cushing's disease and TSH-secreting adenomas.

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Why is it important?

FIPA is the most common form of familial/inherited pituitary adenomas and after the publication of this study allowed many FIPA patients to be identified worldwide.