Fat in the neck can produce heat

What is it about?

We demonstrate in a large animal that brown adipose tissue mitochondrial uncoupling protein is highly abundant in sternal adipose tissue and could contribute to the thermogenic response to feeding.

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Why is it important?

The extent to which sternal fat expansion, and particularly uncoupling protein 1 abundance, can be modulated in early life may inform new strategies to manipulate energy balance, especially following feeding or in response to chronic food restriction during adulthood.